Estimating Renal Function for Drug Dosing: Rewriting the Gospel?
AbstractOne of the hospital pharmacist’s many clinical roles is to estimate renal function, refer to literature references, and adjust medication doses for renal dysfunction. Use of the Cockcroft–Gault (CG) equation for this purpose has long been pharmacists’ “11th commandment”. Recently, however, the increasing availability of estimates of glomerular filtration rate (GFR) from clinical laboratories has led some to call for this commandment to be rewritten.1-3 In this paper, we examine this issue and give readers a suggestion for what we think the “new gospel” should entail.
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